Resveratrol And Human Obesity… Tested

Obesity is a major problem in Western cultures, increasing the likelihood of diseases such as diabetes, cardiovascular disease, cancer and osteoarthritis.

A simple solution may be to eat less, in what is known in the scientific community and caloric restriction. It is well documented in several animal and cellular models, that a 30-50% calorie restriction, not only can reduce the incidence of cancer and diabetes, but also improve resistance to stress and reduce other age-related functional capacity decreases and mental.

What is remarkable about calorie restriction is that once your body gets used to lower calories, physiologically operates more efficiently and acquire improved metabolic profile. These and other observations have led to studies with the goal of finding compounds that can mimic caloric restriction without having to cut calories.

Resveratrol is a compound with the ability to activate the same proteins also activated when animals or cells were subjected to caloric restriction, which is remarkable. However, although many studies have been conducted on human cells, few studies have been conducted in humans.

In a study published in the journal Cell Metabolism, researchers did just that (Cell Metabolism, 2011, vol. 14 page 612). The researchers gave obese people (but who otherwise do not suffer from any other condition), a dietary supplement of trans-resveratrol from more than thirty days and then examines various physiological parameters, including the cost of the whole body , energy, fat storage and the ability of fat tissue to the molecules of fat breakdown.

What became apparent and important in the study was that the data showed important changes that were seen in caloric restriction. Within thirty days resveratrol was able to reduce energy expenditure, improve the metabolic profile and improve general health parameters (such as decreased glucose concentrations , insulin and triglycerides in the blood).

Tags: Caloric Restriction, Calorie Restriction, dietary supplement, general health, glucose concentrations, human obesity, metabolic profile